Publikationen


2023
Dötsch, A.; Merz, B.; Louis, S.; Krems, C.; Herrmann, M.; Dörr, C.; Watzl, B.; Bub, A.; Straßburg, A.; Engelbert, A. K. (2023). Assessment of Energy and Nutrient Intake and the Intestinal Microbiome (ErNst Study): Protocol and Methods of a Cross-sectional Human Observational Study. JMIR Research Protocols, 12, Art.-Nr.: e42529. doi:10.2196/42529VolltextVolltext der Publikation als PDF-Dokument
Kistner, S.; Mack, C. I.; Rist, M. J.; Krüger, R.; Egert, B.; Biniaminov, N.; Engelbert, A. K.; Seifert, S.; Dörr, C.; Ferrario, P. G.; Neumann, R.; Altmann, S.; Bub, A. (2023). Acute effects of moderate vs. vigorous endurance exercise on urinary metabolites in healthy, young men : A multi-platform metabolomics approach. Frontiers in physiology, 14, Article no: 1028643. doi:10.3389/fphys.2023.1028643VolltextVolltext der Publikation als PDF-Dokument
2021
Danesi, F.; Mengucci, C.; Vita, S.; Bub, A.; Seifert, S.; Malpuech-Brugère, C.; Richard, R.; Orfila, C.; Sutulic, S.; Ricciardiello, L.; Marcato, E.; Capozzi, F.; Bordoni, A. (2021). Unveiling the Correlation between Inadequate Energy/Macronutrient Intake and Clinical Alterations in Volunteers at Risk of Metabolic Syndrome by a Predictive Model. Nutrients, 13 (4), Article no: 1377. doi:10.3390/nu13041377VolltextVolltext der Publikation als PDF-Dokument
Kistner, S.; Döring, M.; Krüger, R.; Rist, M. J.; Weinert, C. H.; Bunzel, D.; Merz, B.; Radloff, K.; Neumann, R.; Härtel, S.; Bub, A. (2021). Sex-specific Relationship between the Cardiorespiratory Fitness and Plasma Metabolite Patterns in Healthy Humans—Results of the KarMeN Study. Metabolites, 11 (7), Art. Nr.: 463. doi:10.3390/metabo11070463VolltextVolltext der Publikation als PDF-Dokument
2019
Bub, A.; Malpuech-Brugère, C.; Orfila, C.; Amat, J.; Arianna, A.; Blot, A.; Di Nunzio, M.; Holmes, M.; Kertész, Z.; Marshall, L.; Nemeth, I.; Ricciardiello, L.; Seifert, S.; Sutulic, S.; Ulaszewska, M.; Bordoni, A. (2019). A Dietary Intervention of Bioactive Enriched Foods Aimed at Adults at Risk of Metabolic Syndrome: Protocol and Results from PATHWAY-27 Pilot Study. Nutrients, 11 (8), 1814. doi:10.3390/nu11081814VolltextVolltext der Publikation als PDF-Dokument
Ghini, V.; Tenori, L.; Capozzi, F.; Luchinat, C.; Bub, A.; Malpuech-Brugere, C.; Orfila, C.; Ricciardiello, L.; Bordoni, A. (2019). DHA-Induced Perturbation of Human Serum Metabolome. Role of the Food Matrix and Co-Administration of Oat β-glucan and Anthocyanins. Nutrients, 12 (1), 86. doi:10.3390/nu12010086VolltextVolltext der Publikation als PDF-Dokument
Mack, C. I.; Egert, B.; Liberto, E.; Weinert, C. H.; Bub, A.; Hoffmann, I.; Bicchi, C.; Kulling, S. E.; Cordero, C. (2019). Robust Markers of Coffee Consumption Identified Amongst the Volatile Organic Compounds in Human Urine. Molecular nutrition & food research, 63 (10), Article: 1801060. doi:10.1002/mnfr.201801060
Ulaszewska, M. M.; Weinert, C. H.; Trimigno, A.; Portmann, R.; Andres Lacueva, C.; Badertscher, R.; Brennan, L.; Brunius, C.; Bub, A.; Capozzi, F.; Cialiè Rosso, M.; Cordero, C. E.; Daniel, H.; Durand, S.; Egert, B.; Ferrario, P. G.; Feskens, E. J. M.; Franceschi, P.; Garcia-Aloy, M.; Giacomoni, F.; Giesbertz, P.; González-Domínguez, R.; Hanhineva, K.; Hemeryck, L. Y.; Kopka, J.; Kulling, S. E.; Llorach, R.; Manach, C.; Mattivi, F.; Migné, C.; Münger, L. H.; Ott, B.; Picone, G.; Pimentel, G.; Pujos-Guillot, E.; Riccadonna, S.; Rist, M. J.; Rombouts, C.; Rubert, J.; Skurk, T.; Sri Harsha, P. S. C.; Van Meulebroek, L.; Vanhaecke, L.; Vázquez-Fresno, R.; Wishart, D.; Vergères, G. (2019). Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies. Molecular nutrition & food research, 63 (1), 1800384. doi:10.1002/mnfr.201800384
Vázquez-Manjarrez, N.; Weinert, C. H.; Ulaszewska, M. M.; Mack, C. I.; Micheau, P.; Pétéra, M.; Durand, S.; Pujos-Guillot, E.; Egert, B.; Mattivi, F.; Bub, A.; Dragsted, L. O.; Kulling, S. E.; Manach, C. (2019). Discovery and Validation of Banana Intake Biomarkers Using Untargeted Metabolomics in Human Intervention and Cross-sectional Studies. The journal of nutrition, 149 (10), 1701–1713. doi:10.1093/jn/nxz125
2018
Armbruster, M.; Rist, M. J.; Seifert, S.; Frommherz, L.; Weinert, C. H.; Mack, C.; Roth, A.; Merz, B.; Bunzel, D.; Krüger, R.; Kulling, S. E.; Watzl, B.; Bub, A. (2018). Metabolite profiles evaluated, according to sex, do not predict resting energy expenditure and lean body mass in healthy non-obese subjects. European journal of nutrition, 1–11. doi:10.1007/s00394-018-1767-1
Mack, C. I.; Weinert, C. H.; Egert, B.; Ferrario, P. G.; Bub, A.; Hoffmann, I.; Watzl, B.; Daniel, H.; Kulling, S. E. (2018). The complex human urinary sugar profile: determinants revealed in the cross-sectional KarMeN study. The American journal of clinical nutrition, 108 (3), 502–516. doi:10.1093/ajcn/nqy131
2017
Krüger, R.; Merz, B.; Rist, M. J.; Ferrario, P. G.; Bub, A.; Kulling, S. E.; Watzl, B. (2017). Associations of current diet with plasma and urine TMAO in the KarMeN study : direct and indirect contributions. Molecular nutrition & food research, 61 (11), Art.Nr. 1700363. doi:10.1002/mnfr.201700363
2016
Bub, A.; Kriebel, A.; Dörr, C.; Bandt, S.; Rist, M. J.; Roth, A.; Hummel, E.; Hoffmann, I.; Kulling, S. E.; Watzl, B. (2016). The Karlsruhe Metabolomics and Nutrition (KarMeN) Study: Protocol and Methods of a cross-sectional study to characterize the metabolome of healthy men and women. Journal of medical internet research / Research Protocols, 5 (3), 146 -. doi:10.2196/resprot.5792
Engelbert, A. K.; Soukup, S. T.; Roth, A.; Hoffmann, N.; Graf, D.; Watzl, B.; Kulling, S. E.; Bub, A. (2016). Isoflavone supplementation in postmenopausal women does not affect leukocyte LDL receptor and scavenger receptor CD36 expression: A double-blind, randomized, placebo-controlled trial. Molecular nutrition & food research, 60 (9), 2008–2019. doi:10.1002/mnfr.201600019
Soukup, S. T.; Helppi, J.; Müller, D. R.; Zierau, O.; Watzl, B.; Vollmer, G.; Diel, P.; Bub, A.; Kulling, S. E. (2016). Phase II metabolism of the soy isoflavones genistein and daidzein in humans, rats and mice: a sex and cross-species comparison. Archives of toxicology, 90 (6), 1335–47. doi:10.1007/s00204-016-1663-5
2015
Cho, G.-S.; König, A.; Seifert, S.; Hanak, A.; Roth, A.; Huch, M.; Bub, A.; Watzl, B.; Franz, C. M. A. P. (2015). Comparative study of the fecal microbiota in patients with type II diabetes after consumption of apple juice for 4 weeks. Food science and biotechnology, 24 (6), 2083–2094. doi:10.1007/s10068-015-0277-7
Souverein, O. W.; De Vries, J. H. M.; Freese, R.; Watzl, B.; Bub, A.; Miller, E. R., III; Castenmiller, J. J. M.; Pasman, W. J.; Van Het Hof, K.; Chopra, M.; Karlsen, A.; Dragsted, L. O.; Winkels, R.; Itsiopoulos, C.; Brazionis, L.; O’Dea, K.; Van Loo-Bouwman, C. A.; Naber, T. H. J.; Van Der Voet, H.; Boshuizen, H. C. (2015). Prediction of fruit and vegetable intake from biomarkers using individual participant data of diet-controlled intervention studies. British journal of nutrition, 113 (9), 1396–1409. doi:10.1017/S0007114515000355
Wiese, S.; Esatbeyoglu, T.; Winterhalter, P.; Kruse, H.-P.; Winkler, S.; Bub, A.; Kulling, S. E. (2015). Comparative biokinetics and metabolism of pure monomeric, dimeric, and polymeric flavan-3-ols: A randomized cross-over study in humans. Molecular nutrition & food research, 59 (4), 610–621. doi:10.1002/mnfr.201400422
2014
Fink, A.; Rüfer, C. E.; Le Grandois, J.; Roth, A.; Aoude-Werner, D.; Marchioni, E.; Bub, A.; Barth, S. W. (2014). Dietary walnut oil modulates liver steatosis in the obese Zucker rat. European journal of nutrition, 53 (2), 645–660. doi:10.1007/s00394-013-0573-z
Graf, D.; Barth, S. W.; Bub, A.; Narr, J.; Rüfer, C. E.; Watzl, B.; Seifert, S. (2014). Dietary fat quality in regular fat diets has minor effects on biomarkers of inflammation in obese Zucker rats. European journal of nutrition, 53 (1), 211–219. doi:10.1007/s00394-013-0518-6
2013
Bode, L. M.; Bunzel, D.; Huch, M.; Cho, G.-S.; Ruhland, D.; Bunzel, M.; Bub, A.; Franz, C. M. A. P.; Kulling, S. E. (2013). In vivo and in vitro metabolism of trans-resveratrol by human gut microbiota. The American journal of clinical nutrition, 97 (2), 295–309. doi:10.3945/ajcn.112.049379
Graf, D.; Seifert, S.; Bub, A.; Fröhling, B.; Dold, S.; Unger, F.; Römpp, A.; Watzl, B. (2013). Anthocyanin-rich juice does not affect gut-associated immunity in Fischer rats. Molecular nutrition & food research, 57 (10), 1753–1761. doi:10.1002/mnfr.201300022
Huch, M.; De Bruyne, K.; Cleenwerck, I.; Bub, A.; Cho, G.-S.; Watzl, B.; Snauwaert, I.; Franz, C. M. A. P.; Vandamme, P. (2013). Streptococcus rubneri sp. nov., isolated from the human throat. International journal of systematic and evolutionary microbiology, 63 (PART 11), 4026–4032. doi:10.1099/ijs.0.048538-0
2012
Barth, S. W.; Koch, T. C. L.; Watzl, B.; Dietrich, H.; Will, F.; Bub, A. (2012). Moderate effects of apple juice consumption on obesity-related markers in obese men: Impact of diet-gene interaction on body fat content. European journal of nutrition, 51 (7), 841–850. doi:10.1007/s00394-011-0264-6
Boeing, H.; Bechthold, A.; Bub, A.; Ellinger, S.; Haller, D.; Kroke, A.; Leschik-Bonnet, E.; Müller, M. J.; Oberritter, H.; Schulze, M.; Stehle, P.; Watzl, B. (2012). Critical review: Vegetables and fruit in the prevention of chronic diseases. European journal of nutrition, 51 (6), 637–663. doi:10.1007/s00394-012-0380-y
2011
Hauder, J.; Winkler, S.; Bub, A.; Rüfer, C. E.; Pignitter, M.; Somoza, V. (2011). LC-MS/MS quantification of sulforaphane and indole-3-carbinol metabolites in human plasma and urine after dietary intake of selenium-fortified broccoli. Journal of agricultural and food chemistry, 59 (15), 8047–8057. doi:10.1021/jf201501x
Hsu, F. C.; Wirtz, M.; Heppel, S. C.; Bogs, J.; Krämer, U.; Khan, M. S.; Bub, A.; Hell, R.; Rausch, T. (2011). Generation of Se-fortified broccoli as functional food : Impact of Se-fertilization on S-metabolism. Plant, Cell & Enviroment, 34 (2), 192–207. doi:10.1111/j.1365-3040.2010.02235.x
Pfeuffer, M.; Fielitz, K.; Laue, C.; Winkler, P.; Rubin, D.; Helwig, U.; Giller, K.; Kammann, J.; Schwedhelm, E.; Böger, R. H.; Bub, A.; Bell, D.; Schrezenmeir, J. (2011). CLA does not impair endothelial function and decreases body weight as compared to sunflower oil in overweight male subjects. Journal of the American College of Nutrition, 30 (1), 19–28. 
Welch, R. W.; Antoine, J. M.; Berta, J. L.; Bub, A.; Vries, J. F. de; Guarner, F.; Hasselwander, O.; Hendriks, H. F. J.; Jäkel, M.; Koletzko, B. V.; Patterson, C. C.; Richelle, M. A.; Skarp, M.; Theis, S.; Vidry, S.; Woodside, J. V. (2011). Guidelines for the design, conduct and reporting of human intervention studies to evaluate the health benefits of foods. British journal of nutrition, 106 (Suppl. 2), 3–15. doi:10.1017/S0007114511003606
2010
Garcia, A. L.; Mohan, R.; Koebnick, C.; Bub, A.; Heuer, T.; Strassner, C.; Groeneveld, M. J.; Katz, N.; Elmadfa, I. (2010). Plasma β-carotene is not a suitable biomarker of fruit and vegetable intake in German subjects with a long-term high consumption of fruits and vegetables. Annals of nutrition & metabolism, 56 (1), 23–30. doi:10.1159/000262295
Stracke, B. A.; Rüfer, C. E.; Bub, A.; Barth, S. W.; Briviba, K. (2010). Epigallocatechingallat - Bioverfügbarkeit und Wirkungen auf den Glucosemetabolismus in Zucker-Ratten. Deutsche Gesellschaft für Ernährung: Abstractband zum 47. Wissenschaftlichen Kongressm, Jena, 11.-12. März 2010, 25/1–1, Deutsche Gesellschaft für Ernährung e.V. (DGE). 
2009
Koch, T. C. L.; Briviba, K.; Watzl, B.; Fähndrich, C.; Bub, A.; Rechkemmer, G.; Barth, S. W. (2009). Prevention of colon carcinogenesis by apple juice in vivo: Impact of juice constituents and obesity. Molecular nutrition & food research, 53 (10), 1289–1302. 
Kressel, G.; Trunz, B.; Bub, A.; Hülsmann, O.; Wolters, M.; Lichtinghagen, R.; Stichenoth, D. . O.; Hahn, A. (2009). Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk. Atherosclerosis, 202 (1), 263–271. 
Rüfer, C.; Kulling, S.; Möseneder, J.; Winterhalter, P.; Bub, A. (2009). Role of plasma lipoproteins in the transport of the soybean isoflavones daidzein and daidzein-7-O-ß-D-glucoside. British journal of nutrition, 102 (6), 793–796. 
Stracke, B.; Ruefer, C. E.; Bub, A.; Briviba, K.; Seifert, S.; Kunz, C.; Watzl, B. (2009). Bioavailability and Nutritional Effects of Carotenoids from Organically and Conventionally Produced Carrots in Healthy Men. British journal of nutrition, 101 (11), 1664–1672. 
Stracke, B.; Ruefer, C. E.; Weibel, F. P.; Bub, A.; Watzl, B. (2009). Three Year Comparison of the Polyphenol Content and Antioxidant Capacity in Organically and Conventionally Produced Apples (variety Golden Delicious). Journal of Agricultural and Food Chemistry, 57 (11), 4598–4605. 
2008
Bub, A. (2008). Prävention von Herkreislauferkrankungen durch Obst und Gemüse. Journal für Ernährungsmedizin, 10 (1), 20–21. 
Bub, A.; Möseneder, J.; Wenzel, G.; Rechkemmer, G.; Briviba, K. (2008). Zeaxanthin is bioavailable from genetically modified zeaxanthin-rich potatoes. European journal of nutrition, 47 (2), 99–103. 
Rüfer, C.; Bub, A.; Möseneder, J.; Winterhalter, P.; Stütz, M.; Kulling, S. (2008). Pharmacokinetics of the soybean isoflavone daidzein in its aglycon and glucoside form in healthy men. American Journal of Clinical Nutrition, 87 (5), 1314–1323. 
Rüfer, C.; Möseneder, J.; Briviba, K.; Rechkemmer, G.; Bub, A. (2008). Biovailability of Astaxanthin Stereoisomers from Wild and Aquacultured Salmon in Healthy Men: a Randomized, Double-Blind Study. British journal of nutrition, 99 (5), 1048–1054. 
Rüfer, C. E.; Möseneder, J.; Winterhalter, P.; Kulling, S. E.; Bub, A. (2008). Rolle der Plasmalipoproteine am Transport von Isoflavonen. Abstracts zum 45. Wissenschaftlichen Kongress, Bonn, 13.-14. März 2008. Hrsg.: P. Stehle, 66/1–1, Deutsche Gesellschaft für Ernährung e.V. (DGE). 
Schnäbele, K.; Briviba, K.; Bub, A.; Pool-Zobel, B.-L.; Rechkemmer, G. (2008). Effects of carrot and tomato juice consumption on faecal markers relevant to colon carcinogenesis in humans. British journal of nutrition, 99 (3), 606–613. 
2005
Briviba, K.; Watzl, B.; Nickel, K.; Kulling, S.; Bös, K.; Härtel, S.; Rechkemmer, G.; Bub, A. (2005). A half-marathon and a marathon run induce oxidative DNA damage, reduce antioxidant capacity to protect DNA against damage and modify immune function in hobby runners. Redox Report, 10 (6), 325–331.